NAVIGATING THE UPS AND DOWNS OF BLOOD SUGAR? WHAT

NAVIGATING

THE UPS AND DOWNS

OF BLOOD SUGAR?

In addition to diet and exercise,

JANUVIA can help you along the way.

WHAT IS

JANUVIA

JANUVIA (jah-NEW-vee-ah) is a once-daily prescription pill

that, along with diet and exercise, helps lower blood sugar

levels in adults with type 2 diabetes.

JANUVIA should not be used in patients with type 1

diabetes. If you have had pancreatitis (inﬂammation of the

pancreas), it is not known if you have a higher chance of

getting it while taking JANUVIA.

SELECTED RISK INFORMATION

ABOUT

JANUVIA

Before you take JANUVIA, tell your doctor about all of your

medical conditions. JANUVIA can cause serious side eects,

including pancreatitis, which may be severe and lead to

death. Before you start taking JANUVIA, tell your doctor if

you’ve ever had pancreatitis. Stop taking JANUVIA and call

your doctor right away if you have pain in your stomach

area (abdomen) that is severe and will not go away. The

pain may be felt going from your abdomen through to your

back. The pain may happen with or without vomiting. These

may be symptoms of pancreatitis.

NAVIGATING

THE UPS AND DOWNS

OF BLOOD SUGAR?

JANUVIA, along with diet and exercise,

helps lower blood sugar in adults with T2D.

SELECTED RISK INFORMATION

ABOUT

JANUVIA

(CONTINUED)

Before you start taking JANUVIA, tell your doctor if you

have ever had heart failure (your heart does not pump

blood well enough) or have problems with your kidneys.

Contact your doctor right away if you have increasing

shortness of breath or trouble breathing (especially when

you lie down); swelling or ﬂuid retention (especially in the

feet, ankles, or legs); an unusually fast increase in weight; or

unusual tiredness. These may be symptoms of heart failure.

Selected Risk Information about JANUVIA is continued

on the next page.

Please read the accompanying Medication Guide for JANUVIA.

The physician Prescribing Information also is available.

SELECTED RISK INFORMATION

ABOUT

JANUVIA

(CONTINUED)

Kidney problems, sometimes requiring dialysis, have been

reported.

Do not take JANUVIA if you are allergic to any of its

ingredients, including sitagliptin. Symptoms of serious

allergic reactions to JANUVIA, including rash, hives, and

swelling of the face, lips, tongue, and throat that may cause

diculty breathing or swallowing, can occur. If you have

any symptoms of a serious allergic reaction, stop taking

JANUVIA and call your doctor right away or get emergency

medical help.

Some people who take medicines called DPP-4 inhibitors

like JANUVIA, may develop joint pain that can be severe.

Call your doctor if you have severe joint pain.

Selected Risk Information about JANUVIA is continued

on the next page.

ABOUT

JANUVIA

• JANUVIA is a once-daily pill

• Along with diet and exercise, it helps lower blood sugar

• JANUVIA, by itself, is not likely to cause blood sugar to

go too low (hypoglycemia), because it works less when

blood sugar is low

• JANUVIA, by itself, is not likely to cause weight gain.

Keeping at your target weight is an important part of

taking care of your diabetes. Most people who took

JANUVIA by itself did not gain weight.

Take JANUVIA exactly as your doctor tells you and

follow your doctor's treatment plan for healthy eating

and exercise.

If you take JANUVIA with another medicine that can

cause low blood sugar, such as a sulfonylurea or insulin,

your risk of getting low blood sugar is higher. The dose

of your sulfonylurea medicine or insulin may need to be

lowered while you use JANUVIA. Signs and symptoms of

low blood sugar may include:

• headache

• drowsiness

• irritability

• hunger

• dizziness

• confusion

• sweating

• feeling jittery

• weakness

• fast heart beat

SOME QUESTIONS TO

ASK YOUR DOCTOR.

Questions About JANUVIA:

• Can

JANUVIA help lower my blood sugar (A1C)?

• H

ow do I take JANUVIA?

• Can my blood sugar go too low while taking JANUVIA?

• Do I still have to manage my diet and exercise r

outine

while taking

JANUVIA?

• If I’m already taking metformin, wh

y do I need another

medicine li

ke JANUVIA?

Questions About Type 2 Diabetes:

• What tests are recommended for someone with t

ype

2 diabetes?

•

What lifestyle changes do you recommend t

o help me

etter manage my type 2 diabetes?

Questions About Your A1C Goals:

• I am doing everything I’ve been told to do,

but I’m still not reaching my A1C goal. Why?

• What is my current A1C?

• What is my goal A1C?

SELECTED RISK INFORMATION

ABOUT

JANUVIA

Your doctor may do blood tests before and during treatment

with JANUVIA to see how well your kidneys are working.

Based on these results, your doctor may change your dose

throat, and headache.

prescription drugs to the FDA. Visit http://www.fda.gov/

medwatch, or call 1-800-FDA-1088.

HOW DOES

JANUVIA

WORK?

Along with diet and exercise, JANUVIA works by

enhancing your body’s own ability to lower blood sugar.

• When your body senses blood sugar is high, JANUVIA

works to help lower it

• And when your body senses blood sugar is low,

JANUVIA works less

• JANUVIA works more when you need it. And less when

you don’t

SOME QUESTIONS TO

ASK YOUR DOCTOR.

Some Common Questions About JANUVIA:

• Can JANUVIA help lower my blood sugar (A1C)?

• How do I take JANUVIA?

• What are the possible risks and side eects of JANUVIA?

• Can my blood sugar go too low while taking JANUVIA?

• Do I still have to manage my diet and exercise routine

while taking JANUVIA?

• If I’m already taking metformin, how might another

medicine like JANUVIA help me?

SELECTED RISK INFORMATION

ABOUT

JANUVIA

(CONTINUED)

Some people who take medicines called DPP-4 inhibitors

like JANUVIA may develop a skin reaction called bullous

pemphigoid that can require treatment in a hospital.

Tell your doctor right away if you develop blisters or the

breakdown of the outer layer of your skin (erosion). Your

doctor may tell you to stop taking JANUVIA.

If you take JANUVIA with another medicine that can cause

low blood sugar (hypoglycemia), such as a sulfonylurea or

insulin, your risk of getting low blood sugar is higher. The

dose of your sulfonylurea medicine or insulin may need to

be lowered while you use JANUVIA. Signs and symptoms

of low blood sugar may include headache, drowsiness,

irritability, hunger, dizziness, confusion, sweating, feeling

jittery, weakness, and fast heart beat.

Your doctor will do blood tests to check how well your

kidneys are working before and during your treatment with

JANUVIA. The most common side eects of JANUVIA are

upper respiratory tract infection, stuy or runny nose and

sore throat, and headache.

You are encouraged to report negative side eects of

prescription drugs to the FDA. Visit http://www.fda.gov/

medwatch, or call 1-800-FDA-1088.

Having trouble paying for your Merck medicine?

Merck may be able to help. www.merckhelps.com

Scan the QR code or visit

januvia.com/special-oers

SAVINGS OFFER

Pay as little as $5 per prescription*

Eligible, privately insured patients may pay as little as $5

per prescription. Maximum savings is $150 per prescription.

The coupon may be redeemed once every 30 days.

Not valid for patients who are uninsured or patients with

Medicare or other Government Program insurance. Not all

patients are eligible. Certain restrictions apply. See Terms

and Conditions.

Please read the accompanying Medication Guide for

JANUVIA and discuss it with your doctor. The physician

Prescribing Information also is available.